13 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... life-threatening Differential ... Myotonic dystrophy - Brain ... Serologic and EMG ... failure - Can be
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Normal Reflexes - Brain ... Hemorrhage • CNS ... and Transient Myasthenia ... Gravis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... More likely to cause ... glucocorticoids - can cause ... #Gravis #diagnosis ... #management #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... nervous system: Brain ... • Infectious: Brain ... Postsynaptic: Myasthenia ... Gravis - Lack
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... nodules, may also see ... RingEnhancing #Lesions #Brain ... #differential # ... diagnosis #causes
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
 Most common cause ... Differential diagnosis ... :  Myasthenia ... gravis: Intermittent ... Multiple Sclerosis: CNS
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
And BMP Normal Values ... acidosis: - CNS ... Neuromuscular weakness ... (GBS, Myasthenia ... gravis) - Obstructive
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
AND lower facial weakness ... Isolated lower, bilateral ... inflammatory cause ... ) • EMG/NCS (rare ... patch alone may be
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... EMG: LMN Signs in ... MRI: Brain, cervical ... conditions listed in differential ... #Sclerosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Hyperreflexia develops later ... out • Brain MRI ... : Check for brain ... #differential