11 results
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential ... Resp/Heme: CHF, valves ... I am weak": • Myopathy ... Diagnosis #causes ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Myopathy: ... • Autoimmune: ... #Differential # ... Diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... life-threatening Differential ... Serologic and EMG ... Gravis #diagnosis #management ... #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Causes of spinal ... spinal cord - Autoimmune ... - Radiation myelopathy ... syndromes #lesions #differential ... #diagnosis #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Summary • an autoimmune ... More likely to cause ... glucocorticoids - can cause ... Gravis #diagnosis #management ... #neurology #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Hyperthyroidism - Autoimmune ... Muscle pain - Weakness ... #nephrology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... - Emergency Causes ... lower extremity weakness ... #diagnosis #causes ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... Electrodiagnostic studies (Ex EMG ... Syndrome #diagnosis #management ... #neurology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Aldolase levels • EMG ... statins - probably caused ... Other Diseases: • PBC ... #rheumatology #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
the spinal cord (Myelopathy ... Weakness: - Weakness ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential