8 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... #Causes #differential ... #diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... complete paralysis of all ... Electrodiagnostic studies - EMG ... management #treatment #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential ... Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... Diagnosis #causes ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... cross-reacts with peripheral ... or the axon of peripheral ... diagnosis #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... cord • Guillain-Barre ... lower extremity weakness ... decompression #CaudaEquina ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... weakness in the ... EMG: LMN Signs in ... conditions listed in differential ... Lateral #Sclerosis #neurology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Examples: - Peripheral ... neuron disease (ALS ... weakness, muscle ... Falls #Diagnosis #Differential ... Evaluation #Geriatrics #Neurology