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diagnosis liver algorithm lfts transaminitis acute causes dili drug enzymes gastroenterology hepatitis hepatocellular idiosyncratic induced interpretation management rvalue
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Hepatocellular and Cholestatic ... • R value = (ALT ... R ≤ 2 = Cholestatic ... Transaminitis #diagnosis #differential ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Hepatitis, TB Cholestatic ... #Differential # ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... poisoning, ETOH Cholestatic ... epithelia: - Cholestasis ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... ALF): • Liver injury ... Hemolysis #liver #chemistry ... #diagnosis #differential ... #Hepatology #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dose dependent injury ... Calculate R-Value ... Mixed DILI • Cholestatic ... Idiosyncratic #differential ... gastroenterology #hepatology
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