29 results
diagnosis hematology management causes oncology neurology cardiology classification disease infectiousdiseases lactate nephrology pulmonary rheumatology signs symptoms syndromes abg acid acidbase
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... , Evans Syndrome ... Defects: Sickle cell anemia
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Can be the first ... Inherited arrhythmia syndromes ... (e.g., long QT syndrome ... more intensive treatment ... #diagnosis #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential ... marrow studies Treatment
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... disease #hemolytic #anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... - Prosthetic valves ... • Tumor lysis syndrome ... polyangiitis • Behçet's syndrome ... Dehydrogenase #Elevated #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... result in severe anemia ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Paraneoplastic effects of SCC ... life-threatening Differential ... Miller Fischer and PCB ... Serologic and EMG ... respiratory failure - Can
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and pernicious anemia ... antibody that works ... • Normal ESR, CRP ... Treatment: • ... Diagnosis #Management #treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can ... Autoantibodies: • WAIHA • CAD ... • PCH • Evans ... (-) hemolytic anemia ... Hematology #Monoclonal #Differential
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