12 results
hematology management classification extravascular hemolytic intravascular treatment abg acid acidbase acidosis agglutinin algorithm base bloodgas cold disease disorders elevation gas
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... anemia • ... Prosthetic heart valves
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... - Drugs (Beta lactam ... #differential # ... #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Differentials? ... And BMP Normal Values ... Diagnosis: Causes ... Renal failure (uremia ... Interpretation #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... disorders (e.g. autoimmune ... Myelofibrosis (MF ... #Diagnosis #Causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Diagnosis: • hemolytic ... Hyperbilirubinemia • Elevated lactate ... CLL (older) • Autoimmune ... younger pts) Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... to bolus these values ... Causes of Lactate ... 30mmHg) - Severe anemia ... #Diagnosis #causes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Cirrhosis, ETOH, autoimmune ... Thalassemia, Sickle cell anemia ... #ProteinGap #differential ... #diagnosis #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... mononeuritis multiplex WORKUP ... recent DAN) • EMG ... Goodpasture's cause ... Renal #Syndromes #differential
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