8 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Iron, B-12, or folate ... deficiency • ... blood loss • Hemolytic ... #Decrease #Diagnosis ... #DM2 #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... Diagnosis Algorithm ... Cold AIHA • PCH ... anemia • ... Prosthetic heart valves
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... without platelet decrease ... #Anemia #Differential ... #workup #hematology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
DeficiencyDecreased ... pregnant have hemolytic ... anemia, or psoriasis ... #differential # ... diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... - Prosthetic valves ... Pneumocystis pneumonia (late ... #diagnosis #Laboratory
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Delivery (DO2) • Decreased ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... HIV, Malaria, Late
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... muscle use • Decreased ... 30mmHg) - Severe anemia