17 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Diagnosis Algorithm ... • Sickle cell ... immune-complex hemolytic anemia ... Prosthetic heart valves
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... e.g., uptake by cells ... to bolus these values ... 30mmHg) - Severe anemia ... #Diagnosis #causes
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hyperbilirubinemia • Elevated lactate ... malignancies - B-cell ... younger pts) Differential ... Disorders Such As ... sensitize red blood cells
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... malignancy • Lactase ... appendages • FMF ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
Evades innate and cell-mediated ... Lymphadenopathy, Malaise, Abdominal ... Weight Loss • Can cause ... Lymphohistiocytosis • Anemia ... 20 mg/kg/d IV/IM
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... Pregnancy • Well-conditioned ... iron deficiency anemia ... Syndrome • Blunt Abdominal
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
system including valves ... in Box E and call ... #Hypotension #Differential ... Intraoperative #Checklist #Diagnosis ... #Management #Workup