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hematology management algorithm anesthesia anesthesiology checklist hemolysis intraoperative oncology abdominal acidosis agglutinin arteritis cardiacarrest chronic classification cold disease elevation extravascular
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... • Sickle cell ... immune-complex hemolytic anemia ... Prosthetic heart valves
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... e.g., uptake by cells ... to bolus these values ... 30mmHg) - Severe anemia ... #Diagnosis #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Hyperbilirubinemia • Elevated lactate ... malignancies - B-cell ... younger pts) Differential ... Disorders Such As ... sensitize red blood cells
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Hypotension - Guidelines for Crises in Anaesthesia Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
system including valves ... in Box E and call ... #Hypotension #Differential ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
• As soon as ... breathing system valves ... CardiacArrest #Checklist #Differential ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
- Differential ... dysfunction • PSC ... malignancy • Lactase ... appendages • FMF ... #Differential #
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... that a one-off value ... Too many cells in ... As with many disease ... #workup #hematology
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