9 results
Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
#Diagnosis #EM ... #IM #Honc #Anemia ... #Differential # ... Workup #Algorithm ... #Normocytic #Ddxof
Pleural Effusion - Workup, Diagnostic Algorithm #Diagnosis #EM #IM #PCC #Pleural #Effusion #Transudative #Exudative #Differential #Algorithm
Pleural Effusion - Workup ... #Diagnosis #EM ... #IM #PCC #Pleural ... Transudative #Exudative #Differential ... Lights #Criteria #Ddxof
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... Myelofibrosis (MF
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hyperbilirubinemia • Elevated lactate ... malignancies - B-cell ... younger pts) Differential ... Disorders Such As ... sensitize red blood cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... 30mmHg) - Severe anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Diagnosis? ... • No CRAB - no anemia ... lytic lesions • Lactate ... myeloma Diagnostic ... #Workup #Hematology