13 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Myelofibrosis (MF ... MD, MSc @AmyChung
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... Disorders Such As ... sensitize red blood cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... 30mmHg) - Severe anemia
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... infographic by Nick Mark MD ... Lactic #Acidosis #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
And BMP Normal Values ... Diagnosis: Causes ... Renal failure (uremia ... Daniyal Hashmi, MD ... Interpretation #Diagnosis
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... malignancy • Lactase ... appendages • FMF ... #Causes #Differential
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... that a one-off value ... normal/high - Chronic ... As with many disease ... #workup #hematology