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hematology algorithm classification polycythemia acidosis ascites autoimmune biliary cholangitis cirrhosis clinicopathology elevation erythrocytosis gap globulin hemolysis hepatitis hodgkins hypertension indications
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... normal or slightly elevated ... Normal early on but elevated ... bile ducts Differential ... #workup #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Hypophostphatemia Laboratory ... #Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... If the value is ... WBC count and differential ... #Workup #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Diagnosis Algorithm ... Elevated Hemoglobin ... Polycythemia - Acquired Causes ... Cardiac/pulmonary disease ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... Others #LFTs #Hepatology ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... specificity to elevated ... #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... of underlying disease ... fluid; brown: elevated ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
to bolus these values ... presentations and disease ... Causes of elevated ... - assess other laboratory ... #Diagnosis #causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential ... values. 3. ... Renal parenchymal disease ... #causes #Differential
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... that a one-off value ... can drive this disease ... As with many disease ... #workup #hematology
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