12 results
rheumatology lupus management acidosis algorithm antibodies associations autoantibodies autoimmune behcet biliary causes cholangitis cirrhosis classification clinicopathology comparison diseases druginduced elevation
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Drug-induced SLE ... biliary cirrhosis (PBC ... Endomyseal antibody (EMA ... #diagnosis #table ... #rheumatology #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Hypophostphatemia Laboratory ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
normal or slightly elevated ... Normal early on but elevated ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... If the value is ... WBC count and differential ... #Workup #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Evolution: Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... sediment, and elevated
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
pathognomonic laboratory ... ) Differential Diagnosis ... Oral aphthae : SLE ... • Arthritis: SLE ... signs #symptoms #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... that a one-off value ... Better call hematology ... some time, let’s see ... #workup #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... again we might see ... to bolus these values ... presentations and disease ... - assess other laboratory
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Elevated Globulin ... Albumin > 4) Work-up ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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