10 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... Primary biliary Cholangitis ... #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... #cholangitis #diagnosis ... #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Algorithm Vascular Causes ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... injury #hepatitis #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Cold AIHA • Alloimmune ... Cold AIHA • PCH ... Prosthetic heart valves ... #Hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Castleman disease • AL ... Cirrhosis, ETOH, autoimmune ... Gap #ProteinGap #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Immunosuppression • Autoimmune ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology
Subglottic stenoses (SGS) during systemic diseases
Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
cartilage Diagnostic Work-up ... Laryngotracheal cancer • Autoimmune ... diseases: AL amyloidosis ... systemic #diseases #differential ... #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Aldolase levels • EMG ... Polymyositis or ALS ... statins - probably caused ... #differential #