13 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... Diagnosis #Management #Hematology ... Manifestations #Workup ... #Algorithm #Ddxof
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Cold AIHA • Alloimmune ... Cold AIHA • PCH ... Prosthetic heart valves ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... - Bone marrow evaluation ... or if a primary hematologic ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... disorders (e.g. autoimmune ... Myelofibrosis (MF ... #hematology #secondary
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... Drug-associated, PCH ... #Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... If the value is ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... that a one-off value ... Better call hematology ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... #diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Corticosteroid use • Autoimmune ... appreciate the value ... count on initial evaluation ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology