8 results
diagnosis hepatology algorithm lfts transaminitis abnormal antibodies associations autoantibodies causes chemistry cholangitis diseases elevated gap globulin hemolysis hepatitis injury interpretation
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... bile ducts Differential ... #Cirrhosis #PBC ... cholangitis #diagnosis #workup ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Extrahepatic - Biliary ... hepatitis: < 1 • Cirrhosis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Duct Stone • Biliary
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Diagnosis #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... Endomyseal antibody (EMA ... diagnosis #table #rheumatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... hepatitis: < 1 • Cirrhosis ... Bilirubin: RBC (hemolysis ... #diagnosis #differential ... #Hepatology #transaminitis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... disease: Cirrhosis ... Gap #ProteinGap #differential ... #diagnosis #hematology
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