14 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... gastric bypass), LFT ... Diagnosis #Causes #Workup ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... disease US — Normal ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Drug-induced AIHA - Abnormal ... Cold AIHA • PCH ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
flow cytometry — GP ... 1 or Type 3) — differentiate ... Gplb receptor • Thrombcytopenia ... Platelet #disorders #hematology ... #hemepath #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
• ALT & AST normal ... • Bilirubin - Normal ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
due to a lack of GP ... due to a lack of GP ... receptor] • Normal ... comparison #table #differential ... #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... If the value is ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gastric tumors • Hematology ... chain assay • An abnormal ... #ProteinGap #differential ... #diagnosis #hematology