10 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... (liver disease) ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value ... By Tina Hang, MD ... Idiosyncratic #differential ... gastroenterology #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... If the value is ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... chain assay • An abnormal ... #diagnosis #hematology