14 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Hypersplenism • Secondary ... (e.g. ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... APS), Secondary
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... underlying disease (eg ... erythematosus [SLE ... • Infection (eg ... with leukopenia, anemia
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Malignancy (e.g ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Type III Often Secondary ... tissue disorder (e.g ... . systemic lupus ... erythematosus (SLE
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... loss (>5 lb; 2.5 kg ... Central nervous system ... enzymes ↑ • Mild anemia ... • New onset SLE
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual ... ) • Acute: