8 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... : • Clinical triad ... tissue disorder (e.g ... . systemic lupus ... classification #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Clinical Features
This infographic provides a mnemonic tool called “WOBBLER” for assessing an ECG (electrocardiogram) in cases of
heart’s conduction system ... • B: Brugada ... SyndromeECG ... Clinical Utility ... Efficiency: Provides a systematic
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... • Presence of systemic ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome,
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g