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diagnosis rheumatology management pediatrics peds primarycare amyloid amyloidosis arms bleeding common cryofibrinogenemia dermatologic differential disorders distribution erythematosus gpa granulomatosis hemeonc
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
features of the rash ... -Worse in the skin ... folds e.g. groin ... Pastia’s lines) #Clinical ... #Dermatology #Peds
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... underlying disease (eg ... • Infection (eg ... #Management #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... • Malignancy (e.g ... Endocrine disorders (e.g ... Chronic B-cell activation
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... antiinflammatory properties e.g ... #Rheumatology # ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... cryoglobulin (CG ... Diagnosis: • + Clinical ... Antiphospholipid syndrome ... #hematology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... LVH, low-voltage EKG ... Inflammation → Macrophage activation ... Diagnostic Testing Blood ... Cardiac Testing: • EKG
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
and pruritus (e.g ... Varies with site, (e.g ... - Trunk - Red, blood-filled ... ; pruritis #dermatology ... #rash #differential
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... maculopapular rash ... infections with skin ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
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