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diagnosis differential treatment causes rheumatology algorithm anemia blood systemic acquired activation bleeding bloodbank cerebritis clinical cns disorders elevatedmcv erythematosus extravascular
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Systemic Symptoms (DRESS ... ) Syndrome Treatment ... Methylprednisolone 0.5 - 1.5 mg/kg ... #Syndrome #Treatment ... #Management #dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... withdrawal • Mild disease ... SinaiBmoreIMRes #DRESS ... #Syndrome #dermatology ... #diagnosis #management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
secondary to Systemic Diseases ... • Any systemic disease ... halt nail growth (e.g ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... (eg, systemic juvenile ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Increased Requirement (e.g ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... hemophilia type (e.g ... #treatment #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
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