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diagnosis differential causes algorithm clinical disease fingers hands management physicalexam raynauds video water activation autoimmune bleeding crisis disorders elevatedmcv erythematosus
Raynaud's Syndrome - Washing off under hot water. Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... Raynaud phenomenon ... and arterioles (e.g ... #Raynauds #Syndrome ... fingers #hands #rheumatology
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 Raynaud's Syndrome - Washing off under hot water wath. Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... Raynaud phenomenon ... and arterioles (e.g ... #Raynauds #Syndrome ... fingers #hands #rheumatology
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 Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Increased Requirement (e.g ... • Pernicious Anemia ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... other pathology (e.g ... (short-acting, e.g ... vasodilators (ERAs ... Renal #Crisis #rheumatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Constitutional disorders, eg ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... diagnosis #causes #hematology
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