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diagnosis rheumatology management differential aih antibodies erythematosus hepatology lupus systemic activation algorithm ana antinuclear arthritis associations autoantibodies causes cerebritis chronic
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
, autoimmune hepatitis ... - Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Alcohol, Viral hepatitis ... disorders (e.g. ... RA, SLE), Post-partum
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... (e.g., severe upper ... use assessment (e.g ... laboratory tests (e.g
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • HIV Autoimmune ... Arthritis • SLE ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... Hepatitis, Primary ... ANA #patterns #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Jaundice - Hepatitis ... GI - Felty syndrome ... Vasculitis (e.g. ... , Behçet's syndrome ... differential #diagnosis #rheumatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... inflammation (eg ... been reported (eg ... Histology Findings (eg
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Non-autoimmune ... • Malignancy (e.g ... Endocrine disorders (e.g ... Noninfectious hepatitis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... diseases: - 10% ... SLE or RA - 5 ... tissue disorder (e.g ... erythematosus (SLE
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... (eg, systemic juvenile ... erythematosus [SLE ... • Infection (eg
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