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diagnosis rheumatology differential management joint activation algorithm approach autoimmune causes conditions dermatology erythematosus extrarticular inflammatory jointpain laboratory lupus macrophage mas
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... , Vasculitis (e.g ... ., PAN) • Seizures ... conditions #joint #pain ... differential #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
joint trauma (e.g ... subchondral bone (e.g ... derangements (e.g ... #MSK #rheumatology ... #approach #workup
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Inflammatory Joint Pain ... • Reactive (e.g ... Enteropathic (e.g ... Sicca) Syndrome ... Enteropathic (e.g
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... (eg, systemic juvenile ... • Infection (eg ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... and lower jaw Treatment ... antiinflammatory properties e.g ... osteoarticular and skin disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Joint pain • Swan ... vein thrombosis Hematologic
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (e.g., polymyalgia ... Chemistry profile (e.g ... , and low back pain ... #laboratory #workup
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Sensitivity to pain ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
substantial muscle pain ... Aldolase levels • EMG ... : Fever, joint pain ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
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