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diagnosis neurology treatment barre hematology pulmonary toxicity amiodarone cardiology cardiomyopathy differential encephalopathy gbs guillainbarre hemeonc hemophagocytic hlh induced leukostasis lung
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Electrodiagnostic studies - EMG ... #Barre #Syndrome ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... changes, stroke symptoms ... unless worrisome EKG ... TLS #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... of diagnosis (e.g ... : (distinct symptoms ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
hypothyroid-induced myopathy, Guillain-Barré ... syndrome (GBS), ... antisynthetase syndrome ... (SAMS-CI) • EMG ... myopathy #diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... than one after symptom ... Electrodiagnostic studies (Ex EMG ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... • EEG: With persistent ... the underlying cause ... with AEDs until cause ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... recent DAN) • EMG ... or serologies + symptoms ... Goodpasture's cause ... differential #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Acute toxicity (e.g ... respiratory distress syndrome ... Chronic toxicity (e.g ... Exclude other causes ... Pulmonary #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... ▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
Peripartum Cardiomyopathy (PPCM) What is PPCM? • A form of acute systolic heart failure that develops late in
of pregnancy (e.g ... Genetic variants (e.g ... deficiencies (e.g ... Consider biomarkers (e.g ... recognition and management
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