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diagnosis rheumatology causes differential management systemic acidosis activation arthritis bruising cerebritis cns cryoglobulinemia cryoglobulins disease elevation hematology high hyperkalemia laboratory
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... • Malignancy (e.g ... Endocrine disorders (e.g ... • Type-I Interferonopathies
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... tissue disorder (e.g ... . systemic lupus ... erythematosus ( ... #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... (eg, systemic juvenile ... SLE], AOSD) • Infection ... (eg, visceral leishmaniasis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(systemic lupus ... erythematosus) ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... Tests for All Types ... (e.g., polymyalgia ... Chemistry profile (e.g
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... presentations and disease ... - Compartment syndrome ... #typeb #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
: syßtemic lupus ... erythematosus ( ... SLE), sickle cell ... antiphospholipid syndrome ... High #Potassium #Classification
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