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differential symptoms management arthritis dermatology disease lupus sle systemic dermatomyositis ra rheumatoid testing vasculitis workup aids antimda5 antimda5dm antinxp2 antinxp2dm
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... lesions Abdominal pain ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
vomiting, Abdominal pain ... ischemia, Acute cor ... Livedo reticularis, Erythematous ... Extrapulmonary #Diagnosis ... #Signs #Symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints ... #Diagnosis #Rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... (interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... systemic lupus erythematosus ... life-threatening causes ... comparison #Table #Diagnosis
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 Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... bacilli to bone/joints ... tissue damage - CXR
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... and fingers, or pain ... #erythematosus ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... #Diagnosis #MSK ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... interphalangeal joints ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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