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differential management symptoms arthritis dermatology disease systemic workup dermatomyositis erythematosus lupus msk oncology ra sle syndrome testing vasculitis antimda5 antimda5dm
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... pain / swelling ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... inflammation tends to cause ... disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... bacterial), acute rheumatic ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... #Symptoms #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
skin lesions + Rheumatic ... pain Clinical ... Diagnosis: ... Rule out other causes ... SAPHO #Syndrome #Rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... (interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
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