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management differential signs symptoms arthritis disease dermatology oncology syndrome algorithm erythematosus lupus msk reactions sle systemic approach blood classification dermatomyositis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Chest Pain - Diagnosis and Workup Algorithm History and Exam Acute life-threatening causes: • Acute myocardial infarction •
Chest Pain - Diagnosis ... life-threatening causes ... Pneumothorax • Pulmonary ... ultrasound • CXR ... #Diagnosis #Algorithm
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... Transverse myelitis • Hematology ... Deconditioning - Pain ... #differential #diagnosis ... #causes #pulmonary
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... neurology, back pain ... cell disease Rheumatology ... discrepancy, multiple joint ... Peds #Pediatrics #Diagnosis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... : Is the pain from ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... Diagnosis: ... Rule out other causes ... SAPHO #Syndrome #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... phenomenon (20%) Joints ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
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