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management differential syndrome oncology arthritis dermatology classification dermatomyositis disease hepatology pain ra rheumatoid systemic vasculitis algorithm antimda5 antimda5dm antinxp2 antinxp2dm
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... (interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... phenomenon (20%) Joints ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... pulmonary TB PE ... bacilli to bone/joints ... tissue damage - CXR
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... #Symptoms #diagnosis ... #rheumatology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... inflammation tends to cause ... disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
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