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management hematology oncology syndromes systemic treatment cd4 conditions criticalcare differentiation erythematosus evaluation extrarticular fungal hivaids hyperacute hypoxemia hypoxia infectiousdiseases lupus
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... - pulmonary opacities ... initiation • Differential ... Diagnosis: Infection ... sepsis), PE, DAH, CHF
Hyperacute Hypoxemia - Workup and Management Differential Diagnosis: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Hyperacute Hypoxemia - Workup ... and Management Differential ... , Flash Pulmonary ... Troponin), ABG, STAT CXR ... Sophia Hayes MD
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... failure, COPD, Lung ... Evaluation: Imaging (CXR ... #workup #diagnosis ... #evaluation #differential
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... • Shrinking lung ... #pain #differential ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... coagulopathy) • CBC w differential ... confirm DAH, r/o infection ... sparing of the lung ... Renal #Syndromes #differential
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... muscle aches, joint ... MC: CNS CSF: • ... change in the lungs ... nails, bronchi, lungs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... vesicular eruption • Joints ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Parvovirus infection ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Arthritis: • Joint ... arthropathy • 90% joints ... #Rheumatology
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