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management medications table treatment comparison dosing antibiotics diagnosis overview review drugs pathophysiology cardiology sideeffects diabetes conversion idsa pain anticoagulation toxicology
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Warfarin and DOAC Pharmacology ... Rivaroxaban - Apixaban - Edoxaban ... Warfarin #DOAC #Pharmacology ... rivaroxaban #apixaban #edoxaban
DOAC Cheat Sheet • Apixaban, Dabigatran, Edoxaban, Rivaroxaban • Renal Dosing • Common Drug interactions •
Apixaban, Dabigatran, Edoxaban ... #dosing #ckd #pharmacology
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
#Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
Rivaroxaban, Apixaban, Edoxaban ... Switching #hematology #pharmacology
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Betrixaban (Bevyxxa), Edoxaban ... anticoagulation #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Hepatic, 80% Renal Edoxaban ... NOAC #Metabolism #Pharmacology
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Rivaroxaban, Apixaban, Edoxaban ... anticoagulation #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
if CrCl < 50) Edoxaban ... Anticoagulation #Hematology #Pharmacology ... Rivaroxaban #Dabigatran #Edoxaban
Choice of anticoagulant for treatment of pulmonary embolism • Malignancy - LMWH • To avoid parenteral
- Rivaroxaban; edoxaban ... anticoagulation #pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
Edoxaban, rivaroxaban ... pathway whereas edoxaban ... Interactions #Table #Pharmacology
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