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causes hyperkalemia pharmacology algorithm high hypokalemia hypomg pathophysiology alkalosis channelblockers chloride druginduced gitelman low magnesium management metabolic neurology seizures syndrome
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... hypokalemia and hypomagnesemia ... overdose) - Sodium ... #Medications #differential ... #diagnosis #nephrology
Potassium Channel Blockers - Medications 1. Cardiovascular Drugs 2. Psychiatric drugs 3. Other drugs 4. Synthetic opioids: Levomethadyl 5. Opium
Potassium Channel ... Blockers - Medications ... Opium alkaloids: ... #Differential # ... Diagnosis #Pharmacology
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... osmotic diuresis - Potassium ... #Causes #diagnosis ... #differential # ... medications #drugs
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... (Heparin) • Sodium-channel ... #hyperkalemia #differential ... #pharmacology #potassium ... #medications #druginduced
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Diagnosis Algorithm ... Toxic: Alcohol, Medication ... , Recreational drugs ... Hyponatremia, Hypomagnesemia ... #Causes #neurology
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... osmotic diuresis, Potassium ... renal disease • Drugs ... #Causes #differential ... #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... reactions Common Drugs ... Medications 2. ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Gitelman syndrome, Hypomagnesemia ... and potassium acid ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... reactions Common Drugs ... Medications 2. ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... ratio 0.5%) Differential ... Gitelman #Syndrome #diagnosis ... #nephrology #management
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