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management hematology oncology chronic hemeonc hemophagocytic hlh leukemia lupus lymphocytic lymphohistiocytosis neurology sle summary syndrome thrombocytopenia algorithm antinxp2 antinxp2dm arthritis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... cells can indicate disease ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... immunophenotype Clinical ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #hemeonc #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary Clinical ... necrosis, Lyme disease ... Treatment: admission ... parenteral Abx, Orthopedics ... patient admitted for treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... Low or absent NK cell ... • Bicytopenia Treatment ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... : • Clinical Suspicion ... Management: • D/c all ... #Management #Treatment ... #Hematology #HemeOnc
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... epilepticus Treatment ... underlying cause • Treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology ... #pathophysiology
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