23 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Enlarged hands ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates osteoblasts and ... lipolysis Signs/Symptoms ... acromegaly, widening of hands ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... condition is rare and ... present between 30 and ... Acromegaly #Signs #Symptoms ... #Diagnosis #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
macrognathia), ↑ hand ... tissue swelling and ... malignancy Pathophysiology ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
awakening • Medial hand ... and elbow pain ... • + elbow flexion ... Syndrome #Diagnosis #pathophysiology ... #signs #symptoms
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
: Pathogenesis and ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
- Pathogenesis and ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
: Pathogenesis and ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
- Pathogenesis and ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Inhibitors: Mechanisms and ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... Diagnosis #Signs #Symptoms