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rheumatology management differential dermatology dermatomyositis acidosis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune coagulation cryoglobulinemia cryoglobulins dic disseminated elevation erythematosus gammopathy hemeonc
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... • Blood tests: Elevated ... Dermatomyositis With Malignancy ... Associated with Malignancy ... #dermatology #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... Causes of elevated ... / hypoxemia -> focus ... drugs, seizures, malignancy ... #typeb #classification
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
trauma, sepsis, malignancy ... fibrinogen • Elevated ... organ damage Clinical ... #Coagulation #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy ... Hodgkin Lymphoma - Clinical ... ) Classification ... Inflammatory marker elevated ... #hematology #oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... cryoglobulins • Elevated ... #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Differential Diagnosis ... Serositis: • Pleural/pericardial ... sediment, and elevated
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Serum IgG4 elevated ... specific) COMMON CLINICAL ... breast, skin DIAGNOSIS ... Mimics: Infectious, malignant ... complement • Classification
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Growers (Runyon Classification ... Growers (Runyon Classification ... Hematologic malignancy ... Lung Disease: • Clinical
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... status Labs: Elevated ... CPK - not always elevated ... Associated with Malignancy
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Clinical Presentation ... Elevated soluble ... trigger: Infections, malignancy ... #Management #Hematology
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