8061 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... >500 ng/mL • Elevated ... soluble CD25 • Elevated ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Elevated LDH 5. ... Elevated beta 2 ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... organ damage Clinical ... treatment #management #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Hyperbilirubinemia • Elevated ... hemolytic #anemia #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated ... MatthewHoMD #Elevated ... INR #Algorithm #Hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Deficiency: MMA elevated ... , Homocysteine elevated ... , Homocysteine elevated ... VitaminB12 #diagnosis #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Time (PT) - Often Elevated ... (PTT) - Often elevated ... inhibitor Both elevated ... Thromboplastin #laboratory #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... sediment, and elevated ... vein thrombosis Hematologic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... → Refer to hematology ... • Nonmalignant hematologic ... Diagnosis #Algorithm #hematology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness • Elevated ... weakness, rash • Elevated ... muscle weakness • Elevated ... Normal or mildly elevated ... diagnosis #comparison #rheumatology