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dermatology hlh lymphohistiocytosis rheumatology anemia antinxp2 antinxp2dm aplastic chronic classification cll cutaneous dermatomyositis differential hemeonc hodgkins igg4 leukemia lymphocytic lymphoma
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... >500 ng/mL • Elevated ... #management #treatment ... #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... gangrenosum, Erythema elevatum ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... Elevated LDH 5. ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Inflammatory marker elevated ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Serum IgG4 elevated ... specific) COMMON CLINICAL ... prostate, breast, skin ... DIAGNOSIS ... #Management #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... Clinical Presentation ... Elevated soluble ... #HLH #Hemophagocytic ... #Management #Hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... status Labs: Elevated ... CPK - not always elevated ... Dermatomyositis #diagnosis ... #management #rheumatology
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