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management rheumatology differential hemophagocytic hlh lymphohistiocytosis alkaline alp behcet brain chronic cll cns crypto cryptococcal disease encephalitis erythematosus hemeonc hyophosphatasia
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
pleocytosis • A mildly elevated ... • Common clinical ... pleocytosis with an elevated ... Acute meningeal signs ... #neurology #meningitis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... >500 ng/mL • Elevated ... soluble CD25 • Elevated ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Elevated LDH 5. ... Elevated beta 2 ... workup #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... respiratory failure • Neurologic ... intracranial pressure - Elevated ... Hyophosphatasia #hepatology ... #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... lesions, aseptic meningitis ... Behcet syndrome (Clinical ... #management #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... sediment, and elevated ... PAC • Aseptic meningitis
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... organism (soap bubble sign ... level is sometimes elevated ... drained at time of diagnosis ... T2 #MRI #Brain #clinical
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... • Common Signs ... Hyperferritinemia - Elevated ... Elevated soluble ... #Management #Hematology
Pseudohyperkalemia vs Reverse Hyperkalemia Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated. Pseudohyperkalemia: This
appear falsely elevated ... • No clinical ... signs of hyperkalemia ... potassium normal or lower ... #Diagnosis
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