20 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... Transaminitis - Differential ... Metabolic: Wilson Disease ... #Differential # ... Diagnosis #causes #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... → Refer to hematology ... for workup, including ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #hepatitis #differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Mild jaundice, Elevated ... #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
normal or slightly elevated ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... cholangitis #diagnosis #workup ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... from subclinical disease ... IgG typically elevated ... regarding need for treatment ... Diagnosis #Management #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... specificity to elevated ... Chronic viral hepatitis ... #differential # ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... of cholestatic disease ... Alcoholic liver disease ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... Normal or slightly elevated ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology