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Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... Mild jaundice, Elevated ... Syndrome (Hemolysis, Elevated ... post-partum • Typical clinical ... Disease #Pregnancy #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... IgG typically elevated ... mild laboratory, clinical ... Diagnosis #Management #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Neuropathy ALP is critical ... intracranial pressure - Elevated ... Hyophosphatasia #hepatology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm aPTT: Intrinsic / Final PT: Extrinsic / Final By
Approach to Elevated ... MatthewHoMD #Elevated ... INR #Algorithm #Hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
Deficiency: MMA elevated ... , Homocysteine elevated ... , Homocysteine elevated ... VitaminB12 #diagnosis #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Time (PT) - Often Elevated ... (PTT) - Often elevated ... inhibitor Both elevated ... Thromboplastin #laboratory #hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... Transaminitis #Elevated ... Diagnosis #causes #hepatology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
• Expected: Elevated ... • Expected: Elevated ... • Elevated as ... Scoring #diagnosis #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Others #LFTs #Hepatology
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