13 results
diagnosis hematology algorithm differential hemophagocytic hlh lymphohistiocytosis acquired anticoagulation apml capillary chronic clarksons classification cll differentiation duration dvt encephalopathy fever
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... adsorption onto cancer ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
thermoregulatory center ... and decrease the elevated ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... if WBC > 5 or elevated ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... >500 ng/mL • Elevated ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... , Cancer chemotherapy ... CSF: Modestly elevated ... An elevated white ... #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... Hemoconcentration: elevated ... #diagnosis #management ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Inflammatory marker elevated ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease • Superficial Venous Thrombosis • Upper
Thromboembolic Disease ... post-thrombotic syndrome ... Thrombophilia • Cancer ... anticoagulation #duration #management ... #length #treatment
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