12 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... → Refer to hematology ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Cholestatic disease ... • Alcoholic hepatitis ... • Pancreatic cancer
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... hemopathies, solid cancers ... hepatomegaly, hepatitis ... #diagnosis #management ... #treatment #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and hepatitis ... Lymphoma or other cancers ... gastric and breast cancer ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Noninfectious hepatitis ... sediment, and elevated ... • Cervical cancer ... Erythematosus #Diagnosis #Rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Criteria: • Elevated ... • Treatment algorithms ... von Willebrand disease ... Summary #treatment #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
predominant HL - The tumor ... Inflammatory marker elevated ... number of sites of disease ... classification #hematology ... #oncology #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Serum IgG4 elevated ... swelling), Küttner tumor ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Elevated Globulin ... Work-up of an Elevated ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... differential #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment algorithm ... From Blood Cancer ... hemochromatosis may have an elevated ... #algorithm #hematology ... #cancer