9 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Low calcium • Treatment ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... Rare: DAH, acute febrile ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... #Diagnosis #Management ... #Pediatrics #Peds ... #Febrile #Infant
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... acute or subacute febrile ... following: • Fever ... >500 ng/mL • Elevated ... Lymphohistiocytosis #diagnosis #management
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Troponin may be elevated ... & Dry) is the treatment ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Inflammatory marker elevated ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology ... #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... consideration in febrile ... Hyperferritinemia - Elevated ... Fever b. ... Elevated soluble
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... which drastically elevates ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management