41 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... , Elevated uric ... Syndrome #TLS #diagnosis ... #management #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... skin syndrome, caused ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP (Hemolysis, Elevated ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
HELLP (Hemolysis, Elevated ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
- Differential Diagnosis ... Auspitz sign, Koebner's ... shaped) lesion with elevated ... Papulosquamous #SkinRash #dermatology ... #Algorithm #causes
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology #dermatology ... #diagnosis
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... dermis Clinical Signs ... - Erosions and crusts ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
and decrease the elevated ... rapidly fatal • Causes ... Identify underlying cause ... #Hyperthermia #comparison ... #diagnosis #management
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
Rapid, increasing signs ... about 95% of NMS cases ... and considerably elevated ... #Diagnosis #Serotonin ... NeurolepticMalignant #Comparison
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... >500 ng/mL • Elevated ... soluble CD25 • Elevated ... #management #treatment ... #hematology