11 results
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... inborn errors of metabolism ... connections and pathophysiology ... #Pediatrics #Metabolism ... #Diagnosis #Algorithm
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Inborn Errors of Metabolism ... diagnosing acute metabolic ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #InbornErrors #Metabolism
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... stimulated by bile ... insult Bilirubin metabolism ... Tests #Laboratory #Metabolism ... Bilirubin #Hepatology #Pathophysiology
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... Excreted into bile ... ducts and common bile ... #Biochemistry #Metabolism ... #pathophysiology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... defects, Glutathione metabolism ... pyropoikilocytes, elliptocytes ... Differential #Diagnosis #Algorithm
Lipoprotein Metabolism

Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
Lipoprotein Metabolism ... lipoproteins (VLDLs) and bile ... #Cholesterol #Metabolism ... #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Excessive vomiting - Metabolic ... increase may cause metabolic ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... usually at a single site ... Classification #pathophysiology ... #differential #algorithm
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
signs below the site ... at or below the site ... at or below the site ... Toxic Metabolic: ... differential #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Shock liver • Metabolic ... ALP - Surface of bile ... - Cholestasis/Bile ... differential #diagnosis #algorithm