61 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
of Severe Acute Liver ... hepatitis - Wilson disease ... Hemochromatosis - Primary ... #Differential #Hepatology ... #Diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Algorithm Symptoms ... of autoimmune disease ... Liver biopsy findings ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... - Bone symptoms ... - Drugs - Primary ... biliary Cholangitis ... #Algorithm #hepatology
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Diagnosis Solid ... disease, Biliary ... Cystadenocarcinoma, Primary ... #Differential #Diagnosis ... #hepatology #Radiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... or higher • Liver ... #workup #hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
congenital - Primary ... biliary cirrhosis ... Nonalcoholic fatty liver ... 14 percent) #Diagnosis ... #Differential #Hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
- Differential Diagnosis ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
IBD • Chronic liver ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... include extrahepatic biliary ... disease; AST, aspartate ... disease; T2DM, ... Abnormal #Algorithm #Hepatology