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diagnosis dermatology management vasculitis algorithm disorders neurology symptoms arteritis behcet classification cord cutaneous dermatologic dermpath disease giantcell granulomatosis hematology manifestations
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... vasculitis (5%): PAN > GPA ... #lesions #diagnosis ... #pathology #lesions ... #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... • Painful skin lesions ... #Polyangiitis #GPA
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... syndrome (Clinical ... disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... vasculitis - GPA ... Vasculopathy #Purpura #Differential ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemic skin lesions ... > PR3 60% • GPA ... and branches • GCA ... Ocular inflammatory lesions-interstitial ... • ANCA (Dx: GPA
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
cell arteritis (GCA ... cell arteritis (GCA ... Diagnosis = clinical ... very remarkable w/differential ... required due to skip lesions
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
ischemic skin lesions ... Elevated ESR and CRP GCA ... develop in pts with GCA ... MPO > PR3 60/ GPA ... maculopapular lesions
Oral / Mouth Lesions and Ulcers (Adult & Elderly) - Differential Diagnosis Algorithm Teeth • GERD (Dissolves
Oral / Mouth Lesions ... and Ulcers (Adult ... & Elderly) - Differential ... polyangiitis (GPA ... Mouth #Disorders #Ulcers
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
: Clinical findings ... • Symptoms and signs ... Corticospinal Tract Lesions ... Non-compressive Spinal Cord Causes ... - Sarcoidosis, Behcet
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... • Infectious causes ... or optic nerve lesions ... management #neurology #differential
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