19 results
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
The idiopathic interstitial ... responses of the lung ... combinations of fibrosis ... #Diagnosis #Radiology ... #Pulmonary #CTChest
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... about imaging findings ... lung disease comes ... lung disease and ... #Pulmonary #CXR
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
Left Shunt - Anatomic ... Disease, Interstitial ... Fibrosis, Interstitial ... Lung Disease ... #differential #diagnosis
On the left a chest film of a patient with UIP due to IPF.
The findings on
The findings on ... volume loss and fibrotic ... reticulation with a lower lobe ... Clinical #Radiology #CXR ... UsualInterstitialPneumonitis #Usual #Interstitial
Pleuroparenchymal Fibroelastosis (PPFE) on Chest CT
47 M with idiopathic pleuroparenchymal fibroelastosis. Typical imaging findings:
- Upper lobe
Typical imaging findings ... subpleural and pleural fibrosis ... Rare - GVHD, lung ... radiology #clinical #pulmonary ... #CXR
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... tends to cause interstitial ... lung disease/pulmonary ... fibrosis (mechanism ... signs #symptoms #diagnosis
Septal thickening
Thickening of the lung interstitium by fluid, fibrous tissue, or infiltration by cells results in
Thickening of the lung ... fluid, fibrous ... lung disease, it ... a predominant finding ... pulmonary edema
Based on the images alone, it is usually not possible to determine the cause of the
findings. ... this is nodular interstitial ... lung disease, that ... #Clinical #Diagnosis ... #Radiology #CXR
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... starting amiodarone treatment ... Characteristic finding ... and confirmatory findings ... macrophages Treatment
On the left a patient who is treated with cytotoxic drugs for a hematologic malignancy.
The radiographic
The radiographic findings ... like idiopathic pulmonary ... interstitial pneumonitis ... consider drug-related lung ... Clinical #Radiology #CTChest